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NCBI Description of AFF4 |
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). |
Community Annotation of AFF4 Add / Edit AFF4: Annotations
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Figure notes
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Data details