AFAP1 Back

actin filament associated protein 1

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NCBI Description of AFAP1

The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of AFAP1 Add / Edit AFAP1: Annotations

No community annotations yet for AFAP1.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


AFAP1 is highly significantly mutated in
AFAP1 is significantly mutated in
AFAP1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for AFAP1