ADRB3 Back

adrenergic, beta-3-, receptor

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NCBI Description of ADRB3

The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ADRB3 is highly significantly mutated in
ADRB3 is significantly mutated in
ADRB3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ADRB3