ADRB1 Back

adrenergic, beta-1-, receptor

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NCBI Description of ADRB1
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADRB1 is highly significantly mutated in
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ADRB1 is significantly mutated in
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ADRB1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ADRB1