ADP-ribosylarginine hydrolase

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NCBI Description of ADPRH

The enzyme encoded by this gene catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-ribosylation cycle. Unlike the rat and mouse enzymes, which require DTT for maximal activity, the human enzyme is DTT-independent.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ADPRH is highly significantly mutated in
ADPRH is significantly mutated in
ADPRH is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ADPRH