ADORA2B Back

adenosine A2b receptor

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NCBI Description of ADORA2B
This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADORA2B is highly significantly mutated in
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ADORA2B is significantly mutated in
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ADORA2B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ADORA2B