ADORA2A Back

adenosine A2a receptor

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NCBI Description of ADORA2A
This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADORA2A is highly significantly mutated in
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ADORA2A is significantly mutated in
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ADORA2A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ADORA2A