ADI1 Back

acireductone dioxygenase 1

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NCBI Description of ADI1

This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADI1 is highly significantly mutated in
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ADI1 is significantly mutated in
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ADI1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ADI1