ADH1B Back

alcohol dehydrogenase 1B (class I), beta polypeptide

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ADH1B

The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.

Community Annotation of ADH1B Add / Edit ADH1B: Annotations

No community annotations yet for ADH1B.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADH1B is highly significantly mutated in
(none)
ADH1B is significantly mutated in
(none)
ADH1B is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ADH1B