ADCYAP1 Back

adenylate cyclase activating polypeptide 1 (pituitary)

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NCBI Description of ADCYAP1
This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADCYAP1 is highly significantly mutated in
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ADCYAP1 is significantly mutated in
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ADCYAP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ADCYAP1