ADCY8 Back

adenylate cyclase 8 (brain)

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NCBI Description of ADCY8

Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase

Community Annotation of ADCY8 Add / Edit ADCY8: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ADCY8 is highly significantly mutated in
ADCY8 is significantly mutated in
ADCY8 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ADCY8