ADCY2 Back

adenylate cyclase 2 (brain)

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NCBI Description of ADCY2

This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ADCY2 is highly significantly mutated in
ADCY2 is significantly mutated in
ADCY2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ADCY2