ADAT1 Back

adenosine deaminase, tRNA-specific 1

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NCBI Description of ADAT1
This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described.

Community Annotation of ADAT1 Add / Edit ADAT1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADAT1 is highly significantly mutated in
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ADAT1 is significantly mutated in
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ADAT1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ADAT1