ADAR Back

adenosine deaminase, RNA-specific

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NCBI Description of ADAR
This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADAR is highly significantly mutated in
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ADAR is significantly mutated in
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ADAR is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ADAR