ADAMTSL4 Back

ADAMTS-like 4

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NCBI Description of ADAMTSL4

This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADAMTSL4 is highly significantly mutated in
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ADAMTSL4 is significantly mutated in
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ADAMTSL4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ADAMTSL4