ADAMTSL1 Back

ADAMTS-like 1

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NCBI Description of ADAMTSL1

This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Community Annotation of ADAMTSL1 Add / Edit ADAMTSL1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADAMTSL1 is highly significantly mutated in
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ADAMTSL1 is significantly mutated in
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ADAMTSL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ADAMTSL1