ADAMTS17 Back

ADAM metallopeptidase with thrombospondin type 1 motif, 17

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NCBI Description of ADAMTS17
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADAMTS17 is highly significantly mutated in
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ADAMTS17 is significantly mutated in
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ADAMTS17 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ADAMTS17