ADAM metallopeptidase with thrombospondin type 1 motif, 16

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ADAMTS16

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS18, another family member.

Community Annotation of ADAMTS16 Add / Edit ADAMTS16: Annotations

No community annotations yet for ADAMTS16.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ADAMTS16 is highly significantly mutated in
ADAMTS16 is significantly mutated in
ADAMTS16 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ADAMTS16