ADAM10 Back

ADAM metallopeptidase domain 10

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NCBI Description of ADAM10
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

Community Annotation of ADAM10 Add / Edit ADAM10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ADAM10 is highly significantly mutated in
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ADAM10 is significantly mutated in
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ADAM10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ADAM10