External References:
Wikipedia
GeneCards
HUGO
COSMIC
Google Scholar
NCBI Description of ACVR1C |
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]. |
Community Annotation of ACVR1C Add / Edit ACVR1C: Annotations
No community annotations yet for ACVR1C.
|
Figure notes
• "Mouse over" a mutation to see details. |
|
Click on a tumor type to see its full list of significant genes.
Data details