ACTR3B Back

ARP3 actin-related protein 3 homolog B (yeast)

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NCBI Description of ACTR3B

This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms.

Community Annotation of ACTR3B Add / Edit ACTR3B: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ACTR3B is highly significantly mutated in
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ACTR3B is significantly mutated in
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ACTR3B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ACTR3B