ACTR3 Back

ARP3 actin-related protein 3 homolog (yeast)

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NCBI Description of ACTR3

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene.

Community Annotation of ACTR3 Add / Edit ACTR3: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ACTR3 is highly significantly mutated in
ACTR3 is significantly mutated in
ACTR3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ACTR3