ACSL6 Back

acyl-CoA synthetase long-chain family member 6

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ACSL6

The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.

Community Annotation of ACSL6 Add / Edit ACSL6: Annotations

No community annotations yet for ACSL6.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ACSL6 is highly significantly mutated in
ACSL6 is significantly mutated in
ACSL6 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ACSL6