ACSL6 Back

acyl-CoA synthetase long-chain family member 6

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NCBI Description of ACSL6
The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.

Community Annotation of ACSL6 Add / Edit ACSL6: Annotations

No community annotations yet for ACSL6.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ACSL6 is highly significantly mutated in
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ACSL6 is significantly mutated in
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ACSL6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ACSL6