ACSL1 Back

acyl-CoA synthetase long-chain family member 1

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NCBI Description of ACSL1
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.

Community Annotation of ACSL1 Add / Edit ACSL1: Annotations

No community annotations yet for ACSL1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ACSL1 is highly significantly mutated in
(none)
ACSL1 is significantly mutated in
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ACSL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ACSL1