ACPP Back

acid phosphatase, prostate

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NCBI Description of ACPP

This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway.

Community Annotation of ACPP Add / Edit ACPP: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ACPP is highly significantly mutated in
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ACPP is significantly mutated in
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ACPP is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ACPP