ACOX2 Back

acyl-Coenzyme A oxidase 2, branched chain

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NCBI Description of ACOX2
The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ACOX2 is highly significantly mutated in
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ACOX2 is significantly mutated in
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ACOX2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ACOX2