ACOT8 Back

acyl-CoA thioesterase 8

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NCBI Description of ACOT8
The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells.

Community Annotation of ACOT8 Add / Edit ACOT8: Annotations

No community annotations yet for ACOT8.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ACOT8 is highly significantly mutated in
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ACOT8 is significantly mutated in
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ACOT8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ACOT8