ACOT13 Back

acyl-CoA thioesterase 13

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NCBI Description of ACOT13

This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of ACOT13 Add / Edit ACOT13: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ACOT13 is highly significantly mutated in
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ACOT13 is significantly mutated in
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ACOT13 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ACOT13