ACOT11 Back

acyl-CoA thioesterase 11

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NCBI Description of ACOT11
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.

Community Annotation of ACOT11 Add / Edit ACOT11: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ACOT11 is highly significantly mutated in
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ACOT11 is significantly mutated in
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ACOT11 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ACOT11