ACAT2 Back

acetyl-Coenzyme A acetyltransferase 2

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NCBI Description of ACAT2

The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ACAT2 is highly significantly mutated in
ACAT2 is significantly mutated in
ACAT2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ACAT2