ABTB1 Back

ankyrin repeat and BTB (POZ) domain containing 1

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NCBI Description of ABTB1
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ABTB1 is highly significantly mutated in
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ABTB1 is significantly mutated in
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ABTB1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ABTB1