ABT1 Back

activator of basal transcription 1

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NCBI Description of ABT1

Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.

Community Annotation of ABT1 Add / Edit ABT1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ABT1 is highly significantly mutated in
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ABT1 is significantly mutated in
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ABT1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ABT1