ABR Back

active BCR-related gene

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NCBI Description of ABR
This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene.

Community Annotation of ABR Add / Edit ABR: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ABR is highly significantly mutated in
(none)
ABR is significantly mutated in
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ABR is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ABR