ABP1 Back

amiloride binding protein 1 (amine oxidase (copper-containing))

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NCBI Description of ABP1
This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of ABP1 Add / Edit ABP1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ABP1 is highly significantly mutated in
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ABP1 is significantly mutated in
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ABP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ABP1