ABCG4 Back

ATP-binding cassette, sub-family G (WHITE), member 4

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NCBI Description of ABCG4

The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined.

Community Annotation of ABCG4 Add / Edit ABCG4: Annotations

No community annotations yet for ABCG4.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ABCG4 is highly significantly mutated in
ABCG4 is significantly mutated in
ABCG4 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ABCG4