ABCG1 Back

ATP-binding cassette, sub-family G (WHITE), member 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ABCG1

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.

Community Annotation of ABCG1 Add / Edit ABCG1: Annotations

No community annotations yet for ABCG1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ABCG1 is highly significantly mutated in
(none)
ABCG1 is significantly mutated in
(none)
ABCG1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ABCG1