ABCF1 Back

ATP-binding cassette, sub-family F (GCN20), member 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ABCF1
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process.

Community Annotation of ABCF1 Add / Edit ABCF1: Annotations

No community annotations yet for ABCF1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ABCF1 is highly significantly mutated in
(none)
ABCF1 is significantly mutated in
(none)
ABCF1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ABCF1