ABCB5 Back

ATP-binding cassette, sub-family B (MDR/TAP), member 5

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NCBI Description of ABCB5

ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ABCB5 is highly significantly mutated in
(none)
ABCB5 is significantly mutated in
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ABCB5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ABCB5