ABCA12 Back

ATP-binding cassette, sub-family A (ABC1), member 12

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NCBI Description of ABCA12
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants.

Community Annotation of ABCA12 Add / Edit ABCA12: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ABCA12 is highly significantly mutated in
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ABCA12 is significantly mutated in
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ABCA12 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ABCA12