AAGAB Back

alpha- and gamma-adaptin binding protein

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NCBI Description of AAGAB
The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively spliced transcript variants have been found for this gene.

Community Annotation of AAGAB Add / Edit AAGAB: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AAGAB is highly significantly mutated in
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AAGAB is significantly mutated in
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AAGAB is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for AAGAB